MACI Procedure | DrBurke
Stem Cell Therapy for Knees

Stem Cell Therapy

MACI Procedure | Stem Cell Transplant

MACI Procedure (autologous cultured chondrocytes on porcine collagen membrane) is a form of Stem Cell Therapy for knees. It is made up of your own (autologous) cells that are expanded and placed onto a film. Your Stem Cell Transplant is placed into the cartilage damaged knee and absorbed back into your own tissue.
The amount of MACI applied depends on the size of the cartilage damage. The MACI film is trimmed by your surgeon to match the size and shape of the damage, to ensure the damaged area is completely covered.

Is The Stem Cell MACI Procedure Right For You?

If you’re interested in discussing the Stem Cell MACI Procedure with Dr. Burke, here are some questions you may want to ask:

  1. What is the source of my knee pain?
  2. Will I be able to resume the activities I enjoy?
  3. Why haven’t previous surgical procedures and treatments been effective for my knee pain?
  4. What treatments are available to help provide pain relief?
  5. What treatments can help restore my active lifestyle over the long term?
  6. What are my next steps?

MACI Knee Surgery

*Limitations of Use

The safety and long-term clinical benefit of the MACI Surgery has only been studied in the knee joint.
The safety and effectiveness of the MACI Knee Surgery have not been proven for patients 55 years old and older.


MACI should not be used if you:
• are allergic to antibiotics such as gentamicin, or materials that come from cow, pig, or ox
• have severe osteoarthritis of the knee, other severe inflammatory conditions, infections in the bone joint and other surrounding tissue, or blood clotting conditions
• have had knee surgery in the past 6 months, not including surgery for obtaining a cartilage biopsy or a surgical procedure to prepare your knee for a MACI implant
• cannot follow Dr. Burke’s prescribed rehabilitation program after your MACI surgery


Consult with Dr. Burke if you have cancer in the area of the cartilage biopsy or implant as the safety of MACI is not known in those cases.
Conditions that existed before your surgery, including meniscus tears, joint instability or alignment problems should be evaluated and treated before or at the same time as the MACI Implant Procedure.
MACI is not recommended if you are pregnant or breastfeeding.
MACI has not been studied in patients younger than 18 or over 55 years of age.


Find out if you are a good candidate for the MACI Knee Surgery Procedure. Call Dr. Burke Orthopedics at (713) 436-3488 to Request a Consultation Appointment.